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Human Models for Neuroscience
For decades, neuroscientists seeking to better understand human neurological conditions and develop new therapies have worked with the obvious limitation that a living patient’s brain is not open for investigation…
Angelika Amon, research pioneer on chromosome imbalance, dies at 53
Angelika Amon, professor of biology and a member of the Koch Institute for Integrative Cancer Research, died on Oct. 29 at age 53, following a two-and-a-half-year battle with ovarian cancer….
Down syndrome symposium highlights clinical, fundamental progress
Whether they are working with patients in clinical trials or with chromosomes in cell cultures, scientists and physicians in the Boston area and beyond are testing a wide variety of…
Team
Research Faculty Li-Huei Tsai, Director Dr. Tsai is the director of the Picower Institute for Learning and Memory, lead investigator of the Aging Brain Initiative at MIT, Picower Professor of…
A path for addressing Alzheimer’s blood-brain barrier impairment
About 25 percent of people have the APOE4 variant of the APOE gene, which puts them at substantially greater risk for Alzheimer’s disease. Almost everyone with Alzheimer’s, and even some…
New method visualizes groups of neurons as they compute
This technique, which can be performed using a simple light microscope, could allow neuroscientists to visualize the activity of circuits within the brain and link them to specific behaviors, says…
Mapping the brain at high resolution
The new technology combines a method for expanding brain tissue, making it possible to image at higher resolution, with a rapid 3-D microscopy technique known as lattice light-sheet microscopy. In…