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Human Models for Neuroscience
For decades, neuroscientists seeking to better understand human neurological conditions and develop new therapies have worked with the obvious limitation that a living patient’s brain is not open for…
Angelika Amon, research pioneer on chromosome imbalance, dies at 53
Angelika Amon, professor of biology and a member of the Koch Institute for Integrative Cancer Research, died on Oct. 29 at age 53, following a two-and-a-half-year battle with ovarian…
Down syndrome symposium highlights clinical, fundamental progress
Whether they are working with patients in clinical trials or with chromosomes in cell cultures, scientists and physicians in the Boston area and beyond are testing a wide variety of…
Team
Research Faculty Angelika Amon, Co-Director Dr. Amon is the Kathleen and Curtis Marble Professor in Cancer Research, Associate Director of the Glenn Labs for the Biology of Aging, and Professor…
A path for addressing Alzheimer’s blood-brain barrier impairment
About 25 percent of people have the APOE4 variant of the APOE gene, which puts them at substantially greater risk for Alzheimer’s disease. Almost everyone with Alzheimer’s, and even some…
New method visualizes groups of neurons as they compute
This technique, which can be performed using a simple light microscope, could allow neuroscientists to visualize the activity of circuits within the brain and link them to specific behaviors, says…
Mapping the brain at high resolution
The new technology combines a method for expanding brain tissue, making it possible to image at higher resolution, with a rapid 3-D microscopy technique known as lattice light-sheet microscopy. In…